Why we need novel breast implants

Surgery for breast cancer is common in Western countries but not reconstruction

Breast cancer is the most common cancer in the US and EU/UK
2.3 million women worldwide were diagnosed with breast cancer in 2020

United Estates
281,550
Europe - 27
355,457
United Kingdom
54,700

Breast cancer surgery

of patients in the UK receive surgical therapy
0 %
of patients in the US are under-70 years old
0 %
of all US women requiring mastectomy are offered breast reconstruction
< 0 %

Breast reconstruction: Current breast reconstruction approaches are not ideal

Current breast reconstruction approaches have issues with donor site morbidity, immuno-compatibility and graft / implant failure

Autologous/fat tissue grafts

Picture 1

Complications

  • Complications for flaps are higher (36-74%) than implants (27-31%)
  • Flap failure
  • Donor site morbidity
  • Fat graft reabsorbed or necrosis

Saline/silicone implants

saline silicone

Complications

  • Capsular contracture (scar tissue distorts breast shape) 
  • Breast pain, infection, changes in nipple and breast sensation
  • Implant leakage or rupture
  • Risk of breast implant-associated anaplastic large cell lymphoma
  • Median lifespan of 10 years